Most sedating antidepressants

Whom it may be suitable for: Those with milder or chronic cases of depression, because it has fewer side effects.Pros: This norepinephrine dopamine reuptake inhibitor (NDRI) is often added on to other antidepressant treatments that lose effectiveness over time or cause sexual dysfunction.

Pros: A very effective SSRI that can be easier to start and stay on than others.

Pros: This SSRI has fewer overall side effects than some antidepressants, but the serotonin-related side effects can be powerful.

Side effects: Nausea, insomnia, headaches, sexual dysfunction, jitteriness, dry mouth, drowsiness.

Side effects: Sedation, fatigue, dry mouth, constipation, increased appetite, weight gain.

Whom it may be suitable for: Depression sufferers with anxiety and insomnia: It’s the most sedating antidepressant.

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